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Collectively, these shared mechanisms support a conceptual framework in which magnesium deficiency acts as a disease-modifying factor that amplifies oxidative stress, mitochondrial vulnerability, inflammation, and fibrogenic signaling across liver disease etiologies

KPV is a three-amino-acid fragment of alpha-melanocyte-stimulating hormone being reviewed for inflammatory bowel disease

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Safety studies For in vitro studies, the cytotoxicity of the agents was assessed using the CCK-8 assay and calcein-AM/propidium iodide (PI) staining