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It has been shown that Akkermansia protects the intestinal barrier by increasing the expression of occludin and zona occludens protein 1, thereby preventing lipopolysaccharide translocation, reducing metabolic endotoxemia-induced inflammation, and attenuating atherosclerotic lesions (Li et al., 2016)

A.CarvalhoC

These sentinel findings confirm the damaging effect of chronic tobacco exposure in determining post-infarction ventricular remodeling

Journal of Ethnopharmacology [Google Scholar] Aqueous extract of Paeoniae Radix Alba (Paeonia lactiflora Pall.) ameliorates DSS-induced colitis in mice by tunning the intestinal physical barrier, immune responses, and microbiota

Clinical cohort analyses confirmed that responding patients exhibited significant enrichment of the IFN-I-NK-DC molecular signature in a microbiota-dependent manner (Lam et al., 2021)