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The chamber is designed to separate the luminal side from the basolateral side of the epithelium and, to assess permeability, molecules are placed in the luminal chamber, and the flux of these markers to the basolateral side is measured as an indicator of permeability of the epithelium [41]

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Lip-1 not only suppresses mitochondrial lipid peroxidation and reduces ROS generation, but also restores GSH, GPX4, and FSP1 levels (Wu et al., 2021a

Firmicutes and Proteobacteria were higher while Bacteroidetes was lower in mice fed by fiber deficiency diet, which eroded the colonic mucus barrier, decreased the level of SCFAs, and disrupted the mucosal barrier integrity (Neumann et al., 2021)

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