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It has been hypothesized that IGF-1 LR3 may support neuronal survival and synaptic plasticity through its interaction with IGF-1R in the central nervous system

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Ipamorelin, the First Selective Growth Hormone Secretagogue Pharmacokinetic-Pharmacodynamic Modeling of Ipamorelin, a Growth Hormone Releasing Peptide, in Human Volunteers Pharmacokinetic Evaluation of Ipamorelin and Other Peptidyl Growth Hormone Secretagogues Influence of Chronic Treatment with the Growth Hormone Secretagogue Ipamorelin in Young Female Rats Ipamorelin is a selective growth hormone secretagogue that has been studied for its interaction with the ghrelin (GHS-R) receptor and its effects on growth hormone signaling pathways