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Clin Cancer Res 10(9):2908-17, 2004

10.1016/j.bbagen.2017.05.019 Biochim Biophys Acta Gen Subj

For instance, decreased SIRT3 was found in the fibroblasts from PD patients and SIRT5 was accumulated in idiopathic PD fibroblast cells, with both these sirtuins being mitochondrial proteins 136

Therefore, the survival of metastatic cells during migration could depend on the level of NADPH generated by either the oxidative PPP or alternative mechanisms induced by AMPK