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On other hand, prooxidant therapies, including ionizing radiation and chemotherapeutic agents, are widely used in clinics, based on the rationale that a further oxidative stimulus added to the constitutive oxidative stress in tumor cells should, in fact, cause the collapse of the antioxidant systems, leading to cell death [6]

Qi X, Ng KT, Lian Q, Li CX, Geng W, Ling CC, Yeung WH, Ma YY, Liu XB, Liu H, et al

10.1016/s0023-6438(95)80008-5 19 BrayF.LaversanneM.SungH.FerlayJ.SiegelR

[DOI] [PubMed] [Google Scholar] Murphy MP, Bayir H, Belousov V, Chang CJ, Davies KJA, Davies MJ, et al