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Oxidized Low-Density Lipoprotein Accumulation in Macrophages Impairs Lipopolysaccharide-Induced Activation of AKT2, ATP Citrate Lyase, Acetyl-Coenzyme A Production, and Inflammatory Gene H3K27 Acetylation

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The low hematological indices together with the observed low Fe 2+ levels suggest a microcytic anaemia in the ART-nave HIV-infected patients and support previous studies that have reported low HB, MCV and MCH in HIV treatment-nave patients compared to patients on ART [32, 33]