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Moreover, inhibition of phosphofructokinase (PFK-1) and PKM2 can drive glycolytic flux toward the PPP, which may also be a major factor involved in the widespread overexpression of PKM2 in cancer cells because of the low catalytic efficiency of PKM2 compared with that of PKM1 [47]

Furthermore, the addition of sulfur elevated the content of sulfur-containing compounds, such as GSH, in the root system, and Cd chelated with these sulfur-containing compounds and transported into the root vesicles thereby reducing the transport of Cd from the root system to the A.G