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Body composition may influence dosing requirements, though weight-based dosing has not been consistently employed in animal studies or limited human applications

DUAL GLUCAGON/GLUCAGON-LIKE PEPTIDE-1 RECEPTOR CO-AGONISTS As part of the ongoing effort to use synergistic effects of gastrointestinal hormones in the treatment of diabetes and obesity, the first GIP/GLP-1 receptor co-agonist was reported in 2013

Conversely, animals who received NSI-189 orally for 4 weeks, following the radiation exposure, showed levels of novel environment exploration on par with control animals