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Lpez-SolsRCastro-BarqueroSDonat-VargasCCorradoMArancibia-RiverosCMartnezMet al

Inoculation of -synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve

The N-terminal domain of -syn is characterized by a series of seven 11-residue imperfect repeats, each based upon a highly conserved KTKEGV hexameric motif that is also observed in the -helical domain of apolipoproteins (Davidson et al., 1998