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How Soon Do You Feel Less Tired After a B12 Injection? B12 Injections for Energy and Mood: Benefits Explained Why Do I Feel Worse After My B12 Injection? PA Relief I Feel Tired All the Time. Do I Need a B12 Shot?: Shawn Veiseh, M.D.: Family Medicine Feeling tired, sluggish, or run down? Vitamin B12 plays a key role in energy production, metabolism, brain function, and red blood cell formation. B12 injections deliver this essential vitamin directly
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