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Table 2 outlines the applications of the GHK peptide with larger bioactive peptides such as CyRL-QN15, LL-37, and AW1 across different wound healing models

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According to a review encompassing several clinical trials involving topical GHK-Cu, the peptide can provide several benefits for the skin, including [4]: Tightening loose skin Reversing thinning of aged skin Improving skin firmness, elasticity, and clarity Reducing fine lines and depth of wrinkles, and improving the structure of aged skin Smoothing rough skin and improve overall skin appearance Protecting against UV and photoaging Reducing photodamage, mottled hyperpigmentation, skin spots, and lesions One randomized controlled trial reported that compared to a control serum, GHK-Cu applied topically twice daily in the course of 8 weeks reduced wrinkle volume by 55.8% and wrinkle depth by 32.8% in 40 female volunteers aged 40 to 65 years [17]

Here are the mechanisms of action of the 8 compounds available in our catalog

In addition, recently it has been hypothesized that it can use alternative intracellular carbon sources, such as -ketobutyrate, through the MCC