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- poate contribui la metabolismul energetic normal, la reducerea oboselii, la functionarea

Bai and Lipski, 2013), although its activation in the DRG neurons was inhibited by GSH (Materazzi et al., 2012) (Table 1)

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SIRT3, a class III HDAC associated with longevity, deacetylates Forkhead box protein O3a (FOXO3a) and promotes transcription of antioxidant enzymes (e.g., manganese superoxide dismutase and catalase), thereby constraining mitochondrial ROS and preserving redox homeostasis [71, 72]