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31 Moreover, mTORC2 regulates CD8 T cell differentiation via the SGK1-Foxo1 axis

In addition, it is thought to have many pharmacological properties including antioxidant, anti-inflammatory, neuroprotective, anti-cancer, anti-anxiety, metabolic, heart, liver and kidney protective, and immune effects

255 Siah1, a critical link between p53 and Wnt/-catenin signaling, regulates -catenin turnover independently of GSK3, and its dysfunction contributes to CRC progression

Notably, hepatic selenoprotein expression was also affected by these factors, suggesting an interrelated modulation between cancer protective and risk factors (116)