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doi: 10.1007/s10753-024-02103-5 146 FengZMengFHuoFZhuYQinYGuiYet al

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The accumulation of excessive ROS due to hazardous chemicals, carcinogens, and mutagenic substances in tobacco can damage mitochondrial DNA, inducing oxidative stress

Transcriptional regulation of cholesterol homeostasis is governed by liver X receptors (LXR and ) and sterol regulatory element-binding transcription factor 2 (SREBP2)