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This activates Ca 2+ /calmodulin-dependent protein kinase II (CaMK2) [120], which in turn stimulates the IKK complex, leading to the activation of the transcription factor NF-B

This persistent oxidative imbalance leads to lipid peroxidation, protein oxidation, and DNA damage, culminating in renal cellular dysfunction and death (9)

Can manipulation of gut microbiota really be transformed into an intervention strategy for cardiovascular disease management

Lactate-induced lactylation of NMNAT1 at lys128 enhances its nuclear localization and maintains the enzyme activity to maintain the nuclear NAD+ salvage pathway and promote the survival of pancreatic cancer cells under glucose deprivation conditions (128)

Huang, Antioxidant function of tea dregs protein hydrolysates in liposomemeat system and its possible action mechanism