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The study emphasizes that specific PKC isozymes, triggered by lipid metabolites and hyperglycemia, contribute to vascular abnormalities such as fibrosis, dysfunction of endothelial and vascular smooth muscle cells (VSMC), monocyte activation, cytokine imbalance, excessive extracellular ROS production, and impaired vascular insulin signaling that contribute significantly to DM associated vascular dysfunction [48]

10.2174/1568005014606053 182 SinghV.AhmadS.RaoG

Ferraro and M

A biopsy instrument can be inserted through the catheter to obtain a biopsy sample (Gomez 2009)