liver glutamine-glutathione Targeting glutamine metabolism in hepatic stellate cells alleviates fibrosis L-Glutamine - LiverTox - NCBI

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[Crossref] [Google Scholar] [PubMed] Franco R, Schoneveld OJ, Pappa A, Panayiotidis MI

The mechanism involves cellular reactive oxidative stress, cell proliferation inhibition, senescence, apoptosis, and regulation of MAPK-ERK1/2 signaling, leading to a reduced number of mature oocytes (111)

Microglia in DBA/2J ONHs demonstrate an upregulation of mitochondrial transcripts with predicted changes to oxidative phosphorylation, and dysregulation of genes involved in glycolysis, gluconeogenesis, and lipid metabolism (86)

Results also demonstrated that the TA, EV, and WT possessed clear phenotypic differences that correlated with their ability (or inability) to recover from H 2 O 2 damage