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Rossing P, Birkenfeld AL, Fioretto P, et al

Preprint at b ioRxiv (2020)

M.HaasH.LavermanP.HrtnaglC.SchrettlM.et al

Because of these severe complications, women of childbearing age with hypertension should be transitioned to safer antihypertensives before conception or as soon as pregnancy is confirmed

Its long duration of action is attributable to slow elimination of pituitary tumor tissue, high affinity binding to pituitary dopamine receptors, and extensive enterohepatic recirculation