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Furthermore, glycogen synthase kinase-3 (GSK-3), when activated, can enhance the stable expression of activating transcription factor 3 (ATF3)

In primary cultured cortical neurons, MPP + induces Akt inactivation in neurons from sEH wild-type mice, but not in neurons from knockout mice

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Thus, a classic trigger point is defined as the presence of discrete focal tenderness located in a palpable taut band of skeletal muscle, which produces both referred regional pain (zone of reference) and a local twitch response

Retrospective case series of paediatric patients referred to national poisons centres also report a lower rate of liver injury and hepatotoxicity in children compared with adults following single acute overdose [5255]