Future research should focus on establishing standardized therapeutic protocols, optimizing combinatorial treatment strategies, and conducting well-designed randomized controlled trials with extended follow-up periods to validate the long-term efficacy and safety profile of stem cell-based therapies for AA
Gallic acid derives from the shikimate pathway, and is probably directly synthesized from 3-dehydroshikimic acid, in the reaction catalysed by the dual activity 3-dehydroquinate dehydratase/shikimate dehydrogenase
Half-life is, in simple terms, the duration it takes until half the particular drug is out of the persons body
When the clinical condition is critical and the potential benefits outweigh the risks, cautious use of the above agents may be considered
Thomas CG, Miller AJ, Westbrook GL (2006) Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons