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158 In PASMCs and PDGF-stimulated PASMCs from PAH patients, PFKFB3 is upregulated, triggering the ERK1/2 pathway through glycolysis-generated lactate, which subsequently activates Calpain-2 and promotes cell proliferation

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[DOI] [Google Scholar] Ray G.W., Liang D., Yang Q., Tan B., Dong X., Chi S., et al

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