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Several studies have also used isolated mitochondria preparations [34, 45, 50], which tend to amplify age-related deficits in mitochondrial function compared to measurements conducted on permeabilized myofibers where the mitochondrial reticulum is maintained [51]

Oxidative stress-induced DNA damage of mouse zygotes triggers G2/M checkpoint and phosphorylates Cdc25 and Cdc2

B.EwaltK.YangX.SchimmelP.et al (2008)

Compared to participants without ASR, those with mild (OR 1.15, 95% CI 1.03-1.28), moderate or significant (OR 1.57, 95% CI 1.32-1.85) ASR had increased risks of poor functional recovery after adjustment for confounders

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