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Furthermore, recent findings suggest that CD38 deficiency protects the heart from I/R injury by activating SIRT1/FOXOs-mediated and Sirt3/FOXO3-mediated anti-oxidative stress pathways [25, 26] (Fig

In particular, given their effectiveness in Cr(VI) reduction and As(III) oxidation, more research is needed to verify their role in Mn(II) and Hg(II) transformation