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The antimicrobial protein REG3A, which is involved in wound healing, acts as a downstream mediator between IL-17 and keratinocytes, enhancing their proliferation and inhibiting their differentiation (Lai et al

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Jedoch besttigen nicht alle Untersuchungen diese Interaktion eindeutig und die bislang verfgbaren unkontrollierten Studien zur klinischen Relevanz beruhen auf sehr kleinen Patientenzahlen und lassen noch keine abschlieenden Empfehlungen zu (17)