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Oral glutathione supplements are considered generally safe but results may be inconsistent due to absorption issues

Zhu G, Zhai P, Liu J et al (2004) Structural basis of Rab5-Rabaptin5 interaction in endocytosis

Supplementary Figure S2C)

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In addition, the GSSG:rGSH in the ER is closely associated with the thiol-disulfide status of cysteine residues in the ER-resident proteins and their folding status [44]