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They include infection of hBECs of the BBB, transcytosis, and also infection of transmigration-competent immune cells which may enter the brain as a Trojan horse. A transwell 3D co-culture of HBMECs with astrocytes and monocytes showed how ZIKV-infected monocytes could cross the BBB to enter brain tissue (Bramley et al., via infected monocytes (Nottet et al., 1996

The information presented summarizes preclinical research and should not be construed as medical advice

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