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Anim., 50, 7683 31

Nat Commun 2019;10:3126

its a step towards supporting bone health, cardiovascular health, and overall well-being

Bypassing major fundamental studies regarding the pharmacokinetics and toxicity of a drug lessens the annual cost of introducing a new drug to the market

To test whether SIRT3-mediated amelioration of HSC response to aging contributes to systemic benefits, bone marrow from Mx1-T3 or Mx1-Cre control mice was transplanted into lethally irradiated young wild-type (WT) recipient mice to allow HSCs overexpressing SIRT3 and control HSCs to repopulate the hematopoietic system of WT recipient mice