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10.1016/j.cell.2014.05.016 196 SpinazzolaA.ViscomiC.Fernandez-VizarraE.CarraraF.D'adamoP.CalvoS.et al (2006)

An of 0.05 was used as a threshold for significance

The main regulators of cholesterol synthesis are sterol regulatory element binding proteins (SREBPs), which transcriptionally control the enzymes involved in the synthesis of sterols [61]