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Because of history of thrombosis following prior central venous catheterization, Participant 4 had been previously tested for two genetic variants associated with increased risk of thrombosis, Factor V Leiden and a prothrombin II variant (G20210A), but neither were detected

BMP-2 and sonic hedgehog have contrary effects on adipocyte-like differentiation of C3H10T1/2 cells

Thus, AR dimerization utilized tunable surfaces that are important for interdomain allostery and were found to be particularly important to bind degenerate DNA sequences, providing an explanation for how AREs that deviate considerably from the optimal textbook sequence in CaP still lead to robust transcriptional outputs

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