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Nivolumab works by significantly reducing the number of non-reactive T cells and increasing the number of activated T cells expressing CD38 ( + tumor infiltrating lymphocytes (TILs) produce cytotoxic compounds and inflammatory cytokines to attack tumors

Nevertheless, Sartini et al

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You may experience: A painful and/or itchy rash that can get very large Swelling Warmth A firm bump under your skin where you received your shot According to the Centers for Disease Control and Prevention (CDC), COVID arm can start a few days to a week or more after getting your shot