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Open Biol (2021) 11:210017

Lu YX, Ju HQ, Liu ZX, Chen DL, Wang Y, Zhao Q, Wu QN, Zeng Zlei, Qiu HB, Hu PS, Wang ZQ, Zhang DS, Wang F, Xu RH (2018) ME1 regulates NADPH homeostasis to promote gastric cancer growth and metastasis

The results confirmed that curcumin tended to have a positive impact on distance covered before feeling tired as shown by an increase ( p = 0.09) of 5.51%, compared with the placebo group, which showed an increase of only 2.29%

The arm is held in slight abduction and in external rotation

As ArfGAP1 is required for LRRK2-induced neuronal toxicity, and ArfGAP1 silencing in neurons is generally well-tolerated [16, 17], ArfGAP1 inhibition may offer an alternative therapeutic target for attenuating LRRK2 activity and toxicity in PD