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These are not obscure edge cases

NO reacts with superoxide anion (O ) to form peroxynitrite (ONOO ), exacerbating oxidative damage and ultimately inducing apoptosis (10)

Cell 24 , 30563068 (2013)

6 Intervention strategies 6.1 Probiotics and prebiotics 6.1.1 The concept of psychobiotics Psychobiotics are defined as live microorganisms that confer mental health benefits to the host when ingested in adequate amounts ( liwka et al., 2025)