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Nrf2 is a transcription factor that regulates the expression of antioxidant proteins that protect against oxidative damage

Eaglesfield R, Fernandez-Vizarra E, Lacko E, Caldwell ST, Sloan NL, Siciarz D, et al

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In this case, the antibody binds to the target and masks a binding site of the naturally occurring ligand, wherein the ligand serves as an effector molecule