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2022) engineered Escherichia coli Nissle 1917 to stably express catalase and SOD, enabling active scavenging of intestinal reactive oxygen species, thereby more effectively repairing the epithelial barrier and modulating the microbiota

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Upon completion of rigorous phase-3 trials, the FDA granted approval for tesamorelin therapy in 2010 in HIV-associated lipodystrophy

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