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In the latter process, the TPP-dependent enzyme 2-hydroxyacyl-CoA lyase 1 (HACL1) catalyzes the cleavage of 3-methyl-branched and straight chain 2-hydroxy long-chain fatty acids (50)

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Several strains of Lactobacillus rhamnosus , such as B10, MTCC1423, GG, can restore intestinal barrier and microbiota composition, thereby reducing oxidative stress-induced inflammation in ALD mice, possibly through the intestinal microRNA194-farnesoid X receptor-fibroblast growth factor 15 signaling pathway [142144]