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Sun L, Liu T, Liu J, Gao C, Zhang X

10.2903/j.efsa.2016.4629 117 Weigand-HellerA

JL: Formal analysis, Methodology, Writing review & editing

Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD