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To test this hypothesis, we used RNA interference (RNAi), characterized the recombinant selenoprotein, and screened inhibitory compounds, including two established antischistosomal drugs that are no longer commonly used, potassium antimonyl tartrate (PAT) and oltipraz (OPZ)

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(Chlorophyta), and Euglena gracilis (Euglenophyceae) all produce chemicals that have been demonstrated to have immunomodulatory effects, increase immune responses, or prevent excessive inflammation