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Intrinsic Factor Inhibiting Conditions Conditions such as autoimmune disease or pernicious anemia cause an inability to make the intrinsic factor that is essential for Vitamin B-12 absorption

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Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): Report from the 2009 NIH International Workshop

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Patients with pernicious anemia who need an active B12 form for faster absorption