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References [i] Teichman, S

In spontaneously hypertensive rats, NW up-regulated CSE expression in the aorta, increased H 2 S production, and alleviated hypertension, vascular remodeling, and inflammation

Future efforts should utilize in vitro dynamic models (such as the hollow-fiber infection model) and animal models to comprehensively understand the PK/PD properties of drugs, thereby enabling dosing regimens that provide maximal synergy while minimizing toxicity and resistance development (Wale et al., 2024)

We further discuss the challenges in the management of brain metastases, as well as providing an overview of current therapies and highlighting innovative research towards developing novel efficacious targeted therapies

YuZ: Investigation, Writing review and editing