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Hepatology (2004) 40:18594

All the other authors declare that they have no competing interests

10.3389/fonc.2020.00120 83 EvsyutinaY.KomkovaI.ZolnikovaO.TkachenkoP.IvashkinV

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The BR domain preferentially binds dsDNA while the ZBD domain binds ssDNA, and proper SPRTN association and activation on DNA is dependent on both regions binding (79)