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In summary, from the observations above, we hypothesize that, because of the photo-oxidation of compounds 1 to 2 , 1 NF first fragments into smaller assemblies, which then reassemble into spherical NPs, 2 NP (Fig

Recent innovations such as phospholipid complexes, nanoparticles, micelles, hydrogels, and liposomes have demonstrated enhanced efficacy and safety profiles, offering new hope for maximizing the clinical benefits of curcumin (21, 23)