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CHAC1 plays a crucial role in the pathogenesis of CAC by promoting the breakdown of GSH

Radiation has been shown to damage tumor vasculature and inhibit angiogenesis (Barker et al

There is evidence in a systematic review that NAC used as adjuvant therapy improves schizophrenia symptoms and may also improve one cognitive domain in the area of working memory [131]

Namely, genetic polymorphism with consequential lack or change in the activity of enzymes involved in detoxification of tobacco smoke, a rich source of free radicals and numerous carcinogens, might represent the determinant of this individual susceptibility