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Model robustness was assessed using Receiver Operating Characteristic - Area Under Curve (ROC-AUC) analysis in MetaboAnalyst software

Finally, Novotny et al

Transcription 2010

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In particular, MPTP intoxication typically downregulates key autophagy regulators (LC3-II, beclin-1, parkin, PINK1), but schisandrin A treatment partially preserved the levels of these proteins, implying that it enhances autophagic clearance of toxic aggregates (59, 60)