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This complexity makes identifying and specifically targeting the most relevant pathways within this vast network difficult, as targeting a single oxidant or source may be insufficient and could potentially interfere with physiological redox signaling, given ROSs crucial dual roles as signaling molecules (as elaborated in Section 2.2) (Cheng et al., 2024)

They will expand the work to Edmonton, Calgary, Winnipeg, Thunder Bay, Ont., and do more research with patients in Saskatoon

doi: 10.1038/gim.2016.202 8

Two independent reviewers extracted the data and assessed the methodological quality of included studies

By subcutaneous injection