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Hirsch EC, Hunot S, Damier P, Brugg B, Faucheux BA, Michel PP, et al

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Puedes encontrarla en Utilizada en combinacin con la acetil-l-carnitina para tratamientos relacionados con enfermedades cardacas y problemas de circulacin debido a su importante Propionil-l-carnitina

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1,2,9 Enzyme deficiencies LC-FAOD is caused by specific enzyme deficiencies in the carnitine shuttle system or the -oxidation spiral 4,12 CPT I CACT CPT II VLCAD TFP LCHAD Compromised LCFA metabolism Dysfunctional conversion of LCFAs into acetyl-CoAs results in 1,2,7,14 Lower ATP production Impaired ketogenesis TCA cycle imbalance Enzyme deficiencies can disrupt the anaplerosis-cataplerosis balance, leading to 1,10,15 : Accumulation of toxic metabolites Lack of replenishing substrates in the TCA intermediate pools Impaired energy production Incomplete TCA cycle processing may impair 1,2,7,9,16 : ATP production Gluconeogenesis References 1

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