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Description

Class: Small-molecule NNMT inhibitor (not a peptide)

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98 The acetyltransferase ACAT1 is upregulated in response to extra palmitic acid (PA) and acetylates GNPAT at K128, which represses tripartite motif-containing 21 (TRIM21)-mediated ubiquitination and degradation of GNPAT

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This type of MG generally has a good prognosis when symptoms are well controlled with treatment

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