In mice, knockout of a single H1 subtype does not cause a pronounced phenotype or significantly affect development, which only becomes compromised when multiple isoforms are inactivated 53,54,55,56
[DOI] [PubMed] [Google Scholar] 37.Benor S, Russell GH, Silver M, Israel EJ, Yuan Q, Winter HS
Biologically, chronic lead exposure induces cardiovascular changes that plausibly promote atrial arrhythmogenesis
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