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Pediatric Use Safety and effectiveness in pediatric patients has not been established

Application in Studies of Glucose Metabolism Disorders and Diabetes Glucose metabolism disorder is a hallmark of diabetes, insulin resistance, and related metabolic diseases

Front Endocrinol

Daratumumab earned approval for monotherapy due to its efficacy, safety profile and durable responses demonstrated in the phase 1/2 GEN501 and the phase 2 SIRIUS clinical trials on heavily pretreated RRMM patients [71, 72]