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Group 4 (DEX + SPAE 800): Received DEX (10 mg/kg, I/P) and SPAE orally at 800 mg/kg/day ( The 400 mg/kg and 800 mg/kg body weight/day doses for Spirulina platensis aqueous extract were selected based on previous studies demonstrating safety and hepatoprotective efficacy in rodent models ( Twenty-four hours after the final treatment following the 28-day study, delivery was conducted under ketamine/xylazine anaesthesia at dosages of 7.5 and 1.0 mg/kg by intraperitoneal infusion ( The liver specimens were preserved in a 10% formalin saline solution for histological analysis

Gord Kerr Author Gordon Kerr is a retired nutrition professional with more than 15 years of experience in the healthcare industry

Mn also facilitates the activation of STING in innate immune activation and antitumor immunity 2,3,134

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